Toward the medical application of non-labeled spectroscopic imaging using ultrashort pulse laser technology
In imaging technology, which supports modern medical treatments, tracing the dynamics of physiologically active small molecular compounds in real time in the living body has become increasingly important.
In recent years, an optical imaging technique called coherent Raman scattering (CRS) microscopy has gained attention because it can help visualize local concentration distributions of molecules at high speeds by label-free laser irradiation.
In this article, we describe a CRS microscope system employing an ultrashort pulse technology and discuss the future prospects of applying such label-free spectroscopic imaging methods in the medical field.
- 1 Tokyo University of Agriculture and Technology